Nanoclay Polymeric Nanocomposite; Smart Catalyst to Synthesize Pharmaceutical Compounds

News Date : 2016-07-21 Visit : 485

Iranian and Turkish researchers produced a nanocatalyst by using clay nanoparticles to be used for pharmaceutical purposes

TEHRAN (INIC)- Iranian researchers in association with their Turkish counterparts synthesized a nanocatalyst by using clay nanoparticles to produce some types of pharmaceutical compounds.

The term 'homogenous catalyst' is used when the catalyst and the reactants are all in a similar phase. These catalysts are still used in chemical industries and sometimes they are strong inorganic acids. The acids are highly toxic and it is very dangerous to work with them. The acids also damage the container during the transportation. The separation of the final product from the catalyst results in the waste of the catalyst due to acid neutralization during the reaction and it causes environmental hazards. Non-homogenous catalysts have been developed to deal with the problems of homogenous catalysts and they have been very warmly welcomed.

Cis-beta-aminoketones are among important organic materials that are widely found in the structure of active pharmaceutical and biological compounds. A nanoclay-based nanocatalyst has been synthesized in this research to produce beta-aminoketones in a faster and easier manner.

Recyclability is the most important characteristics of the synthesized nanocatalyst, which results in significant decrease in environmental hazards. The most important innovation in this research is the synthesis of a smart nanocatalyst for Mannich Reaction, which produces various products under different conditions. In similar methods, products are obtained only in one form.

Results of the research have been published in Journal of Iranian Chemical Society, vol. 13, issue 4, 2016, pp. 609-615.